Key result
Pre-operative B-type natriuretic peptide stratification independently predicted major adverse cardiac events (OR 25, 95% CI 8.7-70 for high-risk class), whereas the revised cardiac risk index did not.
Why the study?
Does pre-operative B-type natriuretic peptide risk stratification improve prediction of major adverse cardiac events compared to the revised cardiac risk index in vascular surgical patients?
Observational (n=850)
Does pre-operative B-type natriuretic peptide risk stratification improve prediction of major adverse cardiac events compared to the revised cardiac risk index in vascular surgical patients?
Odds Ratio: 25 (95% CI 8.7–70)
Pre-operative BNP risk stratification is a superior and independent predictor of major adverse cardiac events in vascular surgical patients compared to the revised cardiac risk index.
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BNP stratification may enhance MACE prediction in vascular surgery patients; hypothesis-generating and requires prospective validation before practice change.
Biccard et al. (2011) conducted an observational in Vascular surgical patients (n=850). Pre-operative B-type natriuretic peptide risk stratification vs. Revised cardiac risk index was evaluated on Major adverse cardiac events (OR 25, 95% CI 8.7-70). Pre-operative B-type natriuretic peptide stratification independently predicted major adverse cardiac events (OR 25, 95% CI 8.7-70 for high-risk class), whereas the revised cardiac risk index did not.
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