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Acute cardiac inflammation may be associated with a malignant Brugada syndrome phenotype, highlighting ongoing debates regarding its pathogenesis and sudden death risk stratification.
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Highlights ongoing debate regarding the pathogenesis and risk stratification of sudden death in Brugada syndrome.
Since the publication of the seminal case series in 1992 of right bundle branch block and persistent ST elevation in the right precordial leads associated with sudden death, there remain significant gaps in our knowledge surrounding Brugada syndrome.1 In particular, debate continues regarding its pathogenesis and has in part contributed to the difficulties in risk stratification of sudden death.
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Li et al. (2017) studied this question. Acute cardiac inflammation may be associated with a malignant Brugada syndrome phenotype, highlighting ongoing debates regarding its pathogenesis and sudden death risk stratification.
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