Key result
Children with congenital heart diseases exhibited significantly lower endurance time to exhaustion (67.0 vs. 127.5 s, p<0.001) and maximal contraction compared to healthy controls.
Why the study?
Does sustained isometric exercise reveal differences in performance and muscle oxygenation in children with congenital heart diseases compared to healthy controls?
Case-Control (n=23)
Does sustained isometric exercise reveal differences in performance and muscle oxygenation in children with congenital heart diseases compared to healthy controls?
Absolute Event Rate: 67% vs 127.5%
p-value: p=<0.001
Children with congenital heart disease exhibit reduced muscle strength and endurance associated with impaired muscle oxygenation and slower reoxygenation during recovery compared to healthy peers.
May inform exercise counseling in congenital heart disease; leaves open whether oxygenation deficits mediate endurance limits in prospective studies.
This study investigated performance, muscle oxygen saturation (StO2), and blood volume (BV) in patients with congenital heart diseases (CHD) and healthy children during and following sustained exercise. Maximal volunteered contraction (MVC) and endurance at 50 % of MVC (time to exhaustion, Tlim) of the knee extensor were measured in nine patients with CHD and 14 healthy control children. Near infrared spectroscopy was used to evaluated StO2 and BV in vastus lateralis. The drop in muscle oxygen saturation (D(mO2)), half time of recovery (T(SR)), and recovery speed to maximal oxygen saturation (Rs) were analyzed. Patients with CHD showed lower MVC (101.0 +/- 6.2 vs. 125.5 +/- 7.4 N x m, p < 0.01) and Tlim (67.0 +/- 7.5 vs. 127.5 +/- 11.1 s, p < 0.001) than control children. StO2 and BV values in both groups were similar at rest and decreased at the onset of contraction. D(mO2) was larger in patients, which reflected pronounced deoxygenation. During recovery, the patients exhibited a longer TSR (25.2 +/- 2.1 vs. 18.4 +/- 2.0 s, p < 0.05) and R(S) (64.6 +/- 5.5 vs. 42.7 +/- 4.6 s, p < 0.01) than control children. We concluded that reduced strength and endurance in patients with CHD were associated with an impairment of StO2 and BV, and a slower reoxygenation during recovery.
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Moalla et al. (2006) conducted a case-control in Congenital heart diseases (n=23). Congenital heart diseases (CHD) vs. Healthy control children was evaluated on Endurance at 50% of MVC (time to exhaustion, Tlim) in seconds (p=<0.001). Children with congenital heart diseases exhibited significantly lower endurance time to exhaustion (67.0 vs. 127.5 s, p<0.001) and maximal contraction compared to healthy controls.
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