Why the study?
The authors sought to explore whether the hypertriglyceridemic waist phenotype could serve as an effective, cheap, and non-invasive test for subclinical atherosclerosis.
Does the hypertriglyceridemic waist (HTGW) phenotype predict subclinical atherosclerosis?
Population
Six published studies evaluating HTGW and subclinical atherosclerosis
Comparison
HTGW phenotype vs absence of HTGW phenotype
Design
Systematic review and meta-analysis
Key result
The hypertriglyceridemic waist phenotype was significantly associated with increased odds of subclinical atherosclerosis (OR 2.39).
Authors
Loading...
HTGW phenotype was associated with subclinical atherosclerosis; supports inexpensive screening but prospective validation needed before practice change.
Meta-Analysis (n=2,136)
Does the hypertriglyceridemic waist (HTGW) phenotype predict subclinical atherosclerosis?
Odds Ratio: 2.39 (95% CI 1.63–3.51)
The hypertriglyceridemic waist phenotype is a simple and inexpensive screening tool that is significantly associated with a 2.4-fold increased odds of subclinical atherosclerosis.
Xiong et al. (2026) conducted a meta-analysis in Subclinical atherosclerosis (n=2,136). Hypertriglyceridemic waist (HTGW) phenotype vs. Individuals without the hypertriglyceridemic waist phenotype was evaluated on Subclinical atherosclerosis (OR 2.39, 95% CI 1.63-3.51). The hypertriglyceridemic waist phenotype was significantly associated with increased odds of subclinical atherosclerosis (OR 2.39).