Key result
Vertebral artery dominance increased basilar artery bending over 10 years compared to non-dominant systems, whereas aging was associated with increased basilar artery length.
Why the study?
The study aimed to longitudinally investigate geometric changes in the basilar artery related to aging and vertebral artery dominance.
Does vertebral artery dominance and aging affect basilar artery bending and length in patients with normal vertebrobasilar arterial systems?
Cohort (n=154)
Single-blind
No
Does vertebral artery dominance and aging affect basilar artery bending and length in patients with normal vertebrobasilar arterial systems?
In a longitudinal analysis over 10 years, vertebral artery dominance was significantly associated with increased basilar artery bending, whereas aging was associated with increased basilar artery length.
Answers are grounded in this paper and cite their sources.
VA dominance and aging may shape basilar morphology over time; leaves open whether surveillance or intervention is warranted in normal systems.
This study aimed to investigate the basilar artery (BA) geometric changes in a longitudinal study. 154 subjects with normal vertebrobasilar arterial systems on magnetic resonance angiography were assigned into two groups: 1) non-dominant vertebral artery (VA) and 2) VA dominance. We defined the dominant VA as either that the VA is 3 millimeters larger in diameter or the VA is connected to BA in a more straight angle. BA imaging was segmented to obtain BA bending length (BABL) and BA length (BAL). A mixed model ANOVA was conducted to investigate the impact of aging and VA dominance on the change of BABL and BAL after 123.6 ± 16.2 months. There was a significant main effect of VA dominance on the change of BABL after about 10 years, F (1,152) = 39.78, p < 0.01. On the other hand, there was a significant main effect of aging on the change of BAL during the same period of time, F (1,152) = 6.64, p = 0.01. Most subjects had an opposite directional relationship between the dominant VA and BA bending (71.3%; p < 0.01). Our study supported the hypothesis that the bending of the BA depends on the dominance of the VA, whereas the increased length of the BA depends on aging.
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Ngo et al. (2020) conducted a cohort in Normal vertebrobasilar arterial systems (n=154). Vertebral artery dominance vs. Non-dominant vertebral artery was evaluated on Basilar artery bending length (BABL) (p=<0.01). Vertebral artery dominance increased basilar artery bending over 10 years compared to non-dominant systems, whereas aging was associated with increased basilar artery length.
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