Total Synthesis of (−)‐Allosecurinine

Safe and secure: An efficient methodology which provides access to homochiral 2,5-cis pyrrolidines in excellent yields starting from chiral alkoxyamine cyclopropanes was used in the total synthesis of (−)-allosecurinine (see scheme). The synthesis proceeds with enantiomeric purity in 15 steps with an overall yield of 5 %. OTf: trifluoromethanesulfonate, Boc: tert-butoxycarbonyl, PG: protecting group.