Key result
The combination of plaque enhancement on contrast-enhanced carotid ultrasonography and unstable plaque on MRI predicted a moderate to large amount of debris during carotid artery stenting with 100% sensitivity and 75% specificity (p = 0.036).
Why the study?
Does preoperative assessment with contrast-enhanced carotid ultrasonography and MRI predict the amount of debris caught during carotid artery stenting in patients with severe carotid artery stenosis?
Observational (n=16)
No
Does preoperative assessment with contrast-enhanced carotid ultrasonography and MRI predict the amount of debris caught during carotid artery stenting in patients with severe carotid artery stenosis?
Effect estimate: Sensitivity 100%, Specificity 75%
p-value: p=0.036
Combining contrast-enhanced carotid ultrasonography with MRI improves the prediction of the amount of embolic debris retrieved during carotid artery stenting compared to either modality alone.
May refine embolic risk stratification before carotid stenting; leaves open prospective validation.
Objective: Contrast-enhanced carotid ultrasonography (CEUS) is a new technique for assessing carotid artery plaques. The present study attempted to demonstrate the association between the findings of CEUS performed prior to carotid artery stenting (CAS) and plaque debris caught during CAS.
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Hagiwara et al. (2017) conducted an observational in Severe stenosis of the carotid artery (n=16). Preoperative plaque vulnerability assessment using combination of CEUS and MRI vs. CEUS alone or MRI alone was evaluated on Prediction of moderate to large amount of debris retrieved during carotid artery stenting (Sensitivity 100%, Specificity 75%, p=0.036). The combination of plaque enhancement on contrast-enhanced carotid ultrasonography and unstable plaque on MRI predicted a moderate to large amount of debris during carotid artery stenting with 100% sensitivity and 75% specificity (p = 0.036).
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