Medical Therapy of Reflux Esophagitis

Editorial Notes1 December 1980Medical Therapy of Reflux EsophagitisDONALD O. CASTELL, M.D.DONALD O. CASTELL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-6-926 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMedical therapy aimed at prevention of gastroesophageal reflux or treatment of the resulting esophagitis has been modified considerably during the past few years. A number of new drugs or new uses for old drugs have been shown in controlled treatment trials to be effective adjuncts in the therapy of this common problem (1-4). The prospect of new forms of therapy for a common problem often raises the possibility for older effective forms of therapy to be forgotten or mislaid. This may create the potential for overuse or abuse of the newer, less well-proven therapies.In this issue, Thanik and colleagues...References1. FARRELLROLINGCASTELL RGD. Cholinergic therapy of chronic heartburn: a controlled trial. Ann Intern Med. 1974;80:573-6. LinkGoogle Scholar2. MCCALLUMIPPOLITICOONEYSTURDEVANT RACR. A controlled trial of metoclopramide in symptomatic gastroesophageal refux. N Engl J Med. 1977;296:354-7. CrossrefMedlineGoogle Scholar3. BEHARBRANDBROWN JDF. Cimetidine in the treatment of symptomatic gastroesophageal reflux: a double blind controlled trial. Gastroenterology. 1978;74:441-8. CrossrefMedlineGoogle Scholar4. STANCIUBENNETT CJ. Alginate/antacid in the reduction of gastroesophageal reflux. Lancet. 1974;1:109-11. CrossrefMedlineGoogle Scholar5. THANIKCHEYASHOKGUTIERREZ KWNJ. Reflux esophagitis: effect of oral bethanechol on symptoms and endoscopic findings. Ann Intern Med. 1980;93:805-8. LinkGoogle Scholar6. CHERNOWCASTELL BD. Diet and heartburn. JAMA. 1979;241:2307-8. CrossrefMedlineGoogle Scholar7. JOHNSONDEMEESTERHAGGITT LTR. Esophageal epithelial response to gastroesophageal reflux: a quantitative study. Am J Dig Dis. 1978;23:498-509. CrossrefMedlineGoogle Scholar8. MALMUDCHARKESLITTLEFIELD LNJ. The mode of action of alginic acid compound in the reduction of gastroesophageal reflux. J Nucl Med. 1979;20:1023-8. MedlineGoogle Scholar9. GRAHAMLANZADORSCH DFE. Symptomatic reflux esophagitis: a double blind controlled comparison of antacids and alginate. Curr Ther Res. 1977:22:653-8. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Digestive Diseases Division Uniformed Services University of the Health Sciences Bethesda, Maryland PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCisapride and ranitidine in the treatment of gastro-oesophageal reflux disease-a comparative randomized double-blind trialComparison of omeprazole and ranitidine in treatment of refractory gastroesophageal reflux disease in patients with gastric acid hypersecretionGastric acid hypersecretion in refractory gastroesophageal reflux diseaseProkinetic Agents: A Key in the Future of GastroenterologySleeping on a wedge diminishes exposure of the esophagus to refluxed acidMedical Therapy for Reflux Esophagitis: 1986 and BeyondDONALD O. CASTELL, M.D.Treatment of Severe Reflux Esophagitis with Cimetidine and MetoclopramideDAVID A. LIEBERMAN, M.D., EMMET B. KEEFFE, M.D.A gastroenterologists view of chest painGastroesophageal Reflux Pathogenesis, Diagnosis, and TherapyJOEL E. RICHTER, M.D., DONALD O. CASTELL, M.D.TUBERCULOUS MENINGITIS IN CHILDHOODGASTRO-OESOPHAGEAL REFLUX IN CHILDREN 1 December 1980Volume 93, Issue 6Page: 926-927KeywordsDrug therapyGastroesophageal reflux disease Issue Published: 1 December 1980 PDF downloadLoading ...