Answers are grounded in this paper and cite their sources.
OBJECTIVE: Explore the feasibility of Treat to Target in the area of psoriasis as seen in other therapeutic areas such as hypertension, hyperlipidemia, diabetes and rheumatoid arthritis. METHODS: Review validated, measurable targets for psoriasis, including physician global assessment (PGA), psoriasis area and severity index (PASI) and dermatology life quality index (DLQI). Examine principles brought forth in the published European consensus on psoriasis and develop a Canadian consensus on Treat to Target in psoriasis. RESULTS: As PASI and DLQI are not routinely used in the community setting, we are recommending target at a PGA of zero (clear). CONCLUSION: Recommend that the target is a PGA of zero (clear) as it provides a simple and measurable result that the patient and physician can clearly understand.
No takes yet. Share an insight, caveat, or question.
Gulliver et al. (2015) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: