Key result
A 23-month-old female with a rare left-sided cardiac angiosarcoma presented with widespread metastases and died of complications 8 months after initial presentation.
Case Report (n=1)
This report describes a unique case of pediatric cardiac angiosarcoma with unusual features including young age, left-sided tumor, and widespread metastases.
Documents aggressive course of rare pediatric left-sided cardiac angiosarcoma; leaves open evidence-based management strategies.
We report the seventh case of angiosarcoma of the heart in a child. The patient was a 23-month-old female who presented for lower extremity limping and underwent open surgical biopsy of the femur. Immediately postoperatively, she developed pericardial tamponade, and a bulky intracardiac mass was discovered as the underlying cause. The mass was composed of highly pleomorphic tumor cells reactive for the endothelial markers CD31, CD34, and factor VIII-related antigen (FVIII-RA). Staging evaluation revealed widespread metastases involving the brain, ovaries, and bone marrow. She died of complications of metastatic disease 8 months following initial presentation. Unusual features of this case include the young age of the patient, left-sided nature of the cardiac tumor, presentation secondary to metastatic disease, and the pattern of metastases. The literature on cardiac angiosarcoma, which is limited to six case reports in the pediatric population, is also reviewed.
No takes yet. Share an insight, caveat, or question.
Booth et al. (2001) conducted a case report in Pediatric angiosarcoma of the heart (n=1). Cardiac angiosarcoma was evaluated on Clinical outcome. A 23-month-old female with a rare left-sided cardiac angiosarcoma presented with widespread metastases and died of complications 8 months after initial presentation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: