Key result
Morphological changes in elastic pulmonary arteries, such as luminal dilation and medial thickening, were too variable to predict the severity of peripheral pulmonary vascular disease.
Why the study?
Do morphological changes in elastic pulmonary arteries reflect the severity of peripheral pulmonary vascular disease in patients with pulmonary hypertension?
Case-Control (n=24)
Do morphological changes in elastic pulmonary arteries reflect the severity of peripheral pulmonary vascular disease in patients with pulmonary hypertension?
Morphological changes in elastic pulmonary arteries are too variable to predict the severity of peripheral pulmonary vascular disease, suggesting intravascular ultrasound is unlikely to differentiate less severe, potentially operable disease.
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Morphological variability in elastic pulmonary arteries limits severity prediction; leaves open whether intravascular ultrasound can assess operability in pulmonary hypertension.
McLeod et al. (1999) conducted a case-control in Pulmonary hypertension (n=24). Pulmonary hypertension vs. Infants who died from sudden infant death syndrome was evaluated on Morphological changes in elastic pulmonary arteries. Morphological changes in elastic pulmonary arteries, such as luminal dilation and medial thickening, were too variable to predict the severity of peripheral pulmonary vascular disease.
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