Key result
Decreasing cardiac sympathetic drive and enhancing vagal tone using neurochemical agents appears promising for treating malignant arrhythmias, though no quantitative data were reported.
Modulating autonomic tone with neurochemical agents to decrease sympathetic drive and enhance vagal tone is a promising strategy for treating malignant arrhythmias.
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Autonomic modulation should not yet change arrhythmia management; hypothesis-generating for quantitative trials.
Verrier et al. (1982) conducted a review in Sudden cardiac death. Neurochemical agents (clonidine, morphine sulphate, l-tryptophan, tyrosine) was evaluated. Decreasing cardiac sympathetic drive and enhancing vagal tone using neurochemical agents appears promising for treating malignant arrhythmias, though no quantitative data were reported.
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