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The uptake of cadmium in vivo into parenchymal and non-parenchymal (sinusoidal) cells of the liver was studied by a cell-separation technique. Liver parenchymal cells accumulate cadmium more readily than do non-parenchymal cells and synthesize metallothionein. It is proposed that cadmium uptake and metabolism from injected CdCl2, is restricted almost exclusively to the liver parenchymal cells.
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Cain et al. (1980) studied this question.
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