Key result
Rapid measurement of B-type natriuretic peptide accurately differentiated congestive heart failure from other causes of acute dyspnea, with a mean concentration of 399.6 pg/ml in heart failure patients versus 84.9 pg/ml in those without.
Why the study?
Does rapid measurement of BNP accurately diagnose congestive heart failure in patients presenting to the emergency department with acute shortness of breath?
Cross-Sectional (n=72)
Blinded to test results
No
Does rapid measurement of BNP accurately diagnose congestive heart failure in patients presenting to the emergency department with acute shortness of breath?
Absolute Event Rate: 399.6% vs 84.9%
p-value: p=<0.001
Rapid measurement of BNP is a highly sensitive and specific test for differentiating heart failure from other causes of dyspnea in the emergency department.
No takes yet. Share an insight, caveat, or question.
May aid ED differentiation of heart failure; leaves open prospective validation before practice change.
Angurana et al. (2011) conducted a cross-sectional in Acute dyspnea (n=72). B-type natriuretic peptide (BNP) measurement vs. No heart failure (non-cardiac dyspnea) was evaluated on Mean plasma BNP concentration (p=<0.001). Rapid measurement of B-type natriuretic peptide accurately differentiated congestive heart failure from other causes of acute dyspnea, with a mean concentration of 399.6 pg/ml in heart failure patients versus 84.9 pg/ml in those without.
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