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July 1, 1998Journal of Clinical EpidemiologyOpen Access

A Population-Based Perspective of Changes in Health-Related Quality of Life After Myocardial Infarction in Older Men and Women

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Key result

Incident myocardial infarction in older adults was associated with a significantly higher rate of decline in physical functioning compared to those without MI (26.4% vs. 11.9%, P=0.001).

Why the study?

Does incident myocardial infarction reduce health-related quality of life in older adults?

Population

2812 men and women 65 years and older living in New Haven, CT

Comparison

Incident myocardial infarction during follow-up vs Subjects without MI

Design

Cohort

Follow-up

Up to 6 years (interviews in 1982, 1985, and 1988)

Authors

CLCarlos F. Mendes de LeonHKHarlan M. KrumholzVVViola Vaccarino

Discussion

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Overview

May warrant closer post-MI functional monitoring in older adults; leaves open causal effects on HRQoL and intervention benefits.

Study Design

Type

Cohort (n=2,812)

Structured PICO

Does incident myocardial infarction reduce health-related quality of life in older adults?

P
Population
2,812 men and women aged 65 years and older living in New Haven, CT, followed from 1982 to 1988 to assess changes in health-related quality of life after myocardial infarction.
E
Exposure
Incident myocardial infarction (MI) during follow-up
C
Comparator
Subjects without MI
O
Outcome
Decline in health-related quality-of-life (HQL) outcomes including self-rated health, depressive symptoms, and physical and social functioningpatient reported

Main Result

Absolute Event Rate: 26.4% vs 11.9%

p-value: p=0.001

Incident myocardial infarction in older adults is associated with a significant decline in physical functioning, particularly in the first year post-MI.

Cite This Study

Leon et al. (1998) conducted a cohort in Myocardial infarction (n=2,812). Myocardial infarction vs. Subjects without myocardial infarction was evaluated on Decline in physical functioning (p=0.001). Incident myocardial infarction in older adults was associated with a significantly higher rate of decline in physical functioning compared to those without MI (26.4% vs. 11.9%, P=0.001).

synapsesocial.com/papers/6a978bd3c6bee409dc76e97ehttps://doi.org/10.1016/s0895-4356(98)00037-7
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Also Consider

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  1. 1Health-Related Quality of Life Among Patients Undergoing Percutaneous Transluminal Coronary Angioplasty1991 · 60 citations
  2. 2Self-Reported Physical Health Among Aged Adults1986 · 262 citations
  3. 3Social support and long-term recovery from coronary artery surgery: Effects on patients and spouses.1993 · 183 citations
  4. 4Effect Sizes for Interpreting Changes in Health Status1989 · 2,410 citations
  5. 5A Guttman Health Scale for the Aged1966 · 1,135 citations