Why the study?
The effects of the insulin-like growth factor system on growth, carcass, egg-laying traits, and diversified selection had not been systematically studied in chickens.
Population
Chickens (Gallus gallus) and chicken primary myoblasts
Design
Evolutionary, expression, association, and in vitro functional study
Key result
Genetic variations in the chicken IGF system, particularly SNPs in IGF2BP3, IGFBP2, 5, and 3, were significantly associated with egg-laying performance, body weight, and muscle development.
Authors
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May enable marker-assisted selection for poultry traits; leaves open functional validation in commercial lines.
Genetic variations in the chicken IGF system are significantly associated with egg-laying performance and growth traits, offering potential markers for breeding selection.
Guo et al. (2022) studied this question. IGF system genetic variations was evaluated on Egg production performance, growth, and skeletal muscle development. Genetic variations in the chicken IGF system, particularly SNPs in IGF2BP3, IGFBP2, 5, and 3, were significantly associated with egg-laying performance, body weight, and muscle development.