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April 25, 1995Proceedings of the National Academy of SciencesOpen Access

Molecular and cytotoxic effects of camptothecin, a topoisomerase I inhibitor, on trypanosomes and Leishmania.

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Authors

ABA L BodleyJohns Hopkins UniversityTSTheresa A. ShapiroJohns Hopkins University

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Bodley et al. (1995) studied this question.

synapsesocial.com/papers/6a97971d2b1871755431c3cehttps://doi.org/10.1073/pnas.92.9.3726
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Current Status of Camptothecin Analogues as Antitumor Agents1993 · 621 citations
  2. 2Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.1984 · 561 citations
  3. 3Total synthesis of natural 20(S)-camptothecin1975 · 95 citations
  4. 4Novobiocin Affinity Purification of a Mitochondrial Type II Topoisomerase from the Trypanosomatid Crithidia fasciculata1989 · 72 citations