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Four flavonoids were isolated from the EtOAc extract ofGentiana algidaPall. The structures of these compounds were elucidated as: patulitrin (1), Isoscoparin (2), swertisin (3), swertiajaponin (4). These compounds were identified on the basis of comparing their NMR datas with those of corresponding compounds in the literature. The cytotoxic activity of all these compounds were investigated on the growth of HepG-2 cells, the result showed that compound 2 have high cytotoxic activity, the IC50value is 47.25g/ml.
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Yang et al. (2014) studied this question.
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