Key result
Early carotid endarterectomy in neurologically stable patients with recently symptomatic severe carotid stenosis previously treated by intravenous thrombolysis does not increase haemorrhagic risk.
Why the study?
Does early carotid endarterectomy increase haemorrhagic risk in patients with recently symptomatic severe carotid stenosis previously treated by intravenous thrombolysis?
Observational
Does early carotid endarterectomy increase haemorrhagic risk in patients with recently symptomatic severe carotid stenosis previously treated by intravenous thrombolysis?
Early carotid endarterectomy appears safe without increased hemorrhagic risk in neurologically stable patients recently treated with intravenous thrombolysis for symptomatic severe carotid stenosis.
Supports early CEA consideration in stable patients; leaves open need for RCTs before practice change.
Carotid endarterectomy reduces the risk of stroke in patients with recently symptomatic stenosis.It is also well established that there is a reduction in benefit from CEA with time from the presenting event. Therefore, the procedure should be done early within two-weeks in neurologically stable patients (3,4). According to our results and the small data available in the medical literature, surgery of recently symptomatic severe carotid stenosis previously treated by IVT should not be delayed. There seems to be no higher haemorrhagic risk once this surgery is applied to patients with a stable neurological status and good clinical recovery after lysis. As large series of patients will be difficult to
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Barroso et al. (2013) conducted an observational in Recently symptomatic severe carotid stenosis previously treated by intravenous thrombolysis. Early Carotid Artery Endarterectomy was evaluated on Haemorrhagic risk. Early carotid endarterectomy in neurologically stable patients with recently symptomatic severe carotid stenosis previously treated by intravenous thrombolysis does not increase haemorrhagic risk.
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