Why the study?
The optimal timing of carotid endarterectomy for symptomatic carotid artery stenosis remains debated, specifically whether urgent intervention within 48 hours is safe compared to early intervention within 2 weeks in the era of modern medical therapy.
Does urgent carotid endarterectomy improve outcomes compared to early carotid endarterectomy in patients with symptomatic ipsilateral carotid artery stenosis?
Does urgent carotid endarterectomy improve outcomes compared to early carotid endarterectomy in patients with symptomatic ipsilateral carotid artery stenosis?
Careful patient selection, considering presenting neurology and modern aggressive medical therapy, is essential when deciding between urgent and early carotid endarterectomy.
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Perform CEA within 2 weeks of symptoms for maximal benefit in symptomatic stenosis; reinforces landmark trial evidence on optimal timing.
Azhar et al. (2020) studied this question.
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