Key result
Early CEA is increasingly targeted within 48 hours for TIA and 7 days for nondisabling stroke.
Why the study?
The appropriate timing for performing carotid endarterectomy within the first 14 days after an index event in patients with symptomatic carotid stenosis remains controversial.
Does urgent carotid endarterectomy (within 48 hours) affect periprocedural risk in patients with symptomatic carotid stenosis compared to later surgery?
Population
Patients with recently symptomatic carotid stenosis across 63 identified articles
Comparison
Urgent CEA within 48 hours vs delayed CEA within 14 days
Design
PRISMA-guided systematic review
Authors
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Ideal CEA timing after SCS within 14 days remains unresolved; leaves open need for prospective trials stratified by index event.
Systematic Review
Does urgent carotid endarterectomy (within 48 hours) affect periprocedural risk in patients with symptomatic carotid stenosis compared to later surgery?
The literature suggests a paradigm shift towards early carotid surgery, specifically targeted within 48 hours if the index event is TIA, and within 7 days if the index event is stroke.
Savardekar et al. (2019) conducted a systematic review in Symptomatic carotid stenosis. Urgent carotid endarterectomy (within 48 hours) vs. Later carotid endarterectomy was evaluated on Periprocedural risk. Early carotid endarterectomy is increasingly targeted within 48 hours for patients with a recent transient ischemic attack and within 7 days for those with a nondisabling stroke.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: