Key result
Intravenous glyceryl trinitrate allowed for placental extraction within 4 minutes in 100% of treated patients with retained placenta, with significant but safe reductions in blood pressure.
Why the study?
Does intravenous glyceryl trinitrate safely facilitate the extraction of retained placenta and avoid the need for general anaesthesia?
Observational (n=41)
No
Does intravenous glyceryl trinitrate safely facilitate the extraction of retained placenta and avoid the need for general anaesthesia?
Intravenous glyceryl trinitrate in doses of 200 μg or less appears efficacious and safe for managing retained placenta, potentially obviating the need for general anaesthesia.
No takes yet. Share an insight, caveat, or question.
May avoid general anaesthesia for retained placenta; leaves open confirmation in randomized trials.
Lowenwirt et al. (1997) conducted an observational in Retained placenta (n=41). Intravenous glyceryl trinitrate vs. General anaesthesia without glyceryl trinitrate was evaluated on Placental extraction within 4 minutes of the first bolus. Intravenous glyceryl trinitrate allowed for placental extraction within 4 minutes in 100% of treated patients with retained placenta, with significant but safe reductions in blood pressure.
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