Cerebrovascular Thrombosis in Patients with Buerger's Disease

Nine cases of cerebrovascular thromboangiitis obliterans were observed among 1700 cases of peripheral thromboangiitis obliterans. These, with 30 acceptable cases from the literature, are analyzed. Smoking appears to activate the disease, which is characterized by, recurrences and remissions of focal cortical signs due to thrombosis of cerebral arteries and cortical granular atrophy. Of my patients, one died. Eight have been followed for 35 to 3 years, and with one exception all are ambulatory. Cessation of smoking is necessary. No other effective treatment is known.