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August 31, 2020Open Access

A modified frozen elephant trunk technique for acute Stanford type A aortic dissection

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Key result

The modified frozen elephant trunk technique for acute Stanford type A aortic dissection resulted in 0% hospital mortality and a significant increase in true lumen diameter distal to the stent graft at 3 months (p=0.01).

Why the study?

Acute Stanford type A aortic dissection is often fatal with no optimal standard treatment, prompting the description and short-term outcome evaluation of a modified frozen elephant trunk technique.

Does the modified frozen elephant trunk technique improve aortic remodeling in patients with acute Stanford type A aortic dissection?

Population

16 patients with acute Stanford type A aortic dissection at Xiamen Heart Center

Comparison

Modified frozen elephant trunk technique

Design

Single-center observational study

Follow-up

3 months after discharge

Authors

SSShibo SongChinese Academy of Medical Sciences & Peking Union Medical CollegePHPo-Yuan HuKun Shan UniversityXWXijie WuXiamen University

Discussion

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Implication

No optimal technique for type A dissection repair; leaves open need for comparative trials before practice change.

Study Design

Type

Observational (n=16)

Multicenter

No

Structured PICO

Does the modified frozen elephant trunk technique improve aortic remodeling in patients with acute Stanford type A aortic dissection?

P
Population
16 patients with acute Stanford type A aortic dissection who underwent a modified frozen elephant trunk technique, followed for 3 months.
I
Intervention
Modified frozen elephant trunk technique
O
Outcome
Diameters of the ascending aorta, aortic arch, and descending aorta on the bifurcation of the pulmonary and abdominal aortas at admission, before discharge, and 3 months after dischargesurrogate

The modified frozen elephant trunk technique is safe and feasible for acute Stanford type A aortic dissection, promoting false lumen thrombosis and aortic remodeling at 3 months.

Limitations

  • Retrospective study
  • Small sample size
  • No control group
  • Single center
  • Short follow-up period
  • Long-term outcomes require further investigation

Cite This Study

Song et al. (2020) conducted an observational in Acute Stanford type A aortic dissection (n=16). Modified frozen elephant trunk technique was evaluated on Changes in aortic diameters and short-term mortality. The modified frozen elephant trunk technique for acute Stanford type A aortic dissection resulted in 0% hospital mortality and a significant increase in true lumen diameter distal to the stent graft at 3 months (p=0.01).

synapsesocial.com/papers/6a97b321d72f642c28a665cehttps://doi.org/10.21203/rs.3.rs-20117/v2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Novel arch fenestrated stent graft for acute Stanford Type A aortic dissection with open antegrade implantation2017 · 32 citations
  2. 2Is the branched graft technique better than the en bloc technique for total aortic arch replacement?2013 · 51 citations
  3. 3Sun's procedure of total arch replacement using a tetrafurcated graft with stented elephant trunk implantation: analysis of early outcome in 398 patients with acute type A aortic dissection.2013 · 77 citations
  4. 4Aortic arch replacement with prophylactic aortic arch debranching during type A acute aortic dissection repair: initial experience with 23 patients☆2011 · 16 citations
  5. 5Use of the frozen elephant trunk technique for type A intramural hematoma2019 · 5 citations