Key result
Anxiety was significantly correlated with elevated c-reactive protein levels (ρ = 0.28, P = 0.005), independent of BMI, age, and sex (P = 0.038) in adults with obesity.
Why the study?
Is anxiety or depression associated with elevated inflammation independent of adiposity in persons with obesity?
Population
100 participants with obesity enrolled in a clinical trial for pharmacological weight loss, mean age 57.8…
Design
Cross-sectional
Authors
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Anxiety/depression may link to inflammation beyond adiposity in obese high-CVD-risk adults; hypothesis-generating, prospective data needed before practice change.
Cross-Sectional (n=100)
Is anxiety or depression associated with elevated inflammation independent of adiposity in persons with obesity?
Effect estimate: ρ = 0.28
p-value: p=0.005
Anxiety, but not depression, is independently associated with elevated systemic inflammation in patients with obesity, suggesting a potential therapeutic target for mitigating CVD risk.
Pierce et al. (2016) conducted a cross-sectional in Obesity (n=100). Anxiety was evaluated on Baseline serum c-reactive protein (CRP) (ρ = 0.28, p=0.005). Anxiety was significantly correlated with elevated c-reactive protein levels (ρ = 0.28, P = 0.005), independent of BMI, age, and sex (P = 0.038) in adults with obesity.
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