Key result
Tachycardia (pulse ≥110/min) significantly increased the risk of VTE-related unfavorable outcomes (OR 12.4) in patients with venous thromboembolism.
Why the study?
This study aimed to analyze clinical outcomes in patients with venous thromboembolism and identify risk factors for unfavorable outcomes, major bleeding, and 30-day all-cause mortality.
What are the risk factors for unfavorable outcomes, major bleeding, and 30-day all-cause mortality in patients with venous thromboembolism?
Observational (n=198)
No
What are the risk factors for unfavorable outcomes, major bleeding, and 30-day all-cause mortality in patients with venous thromboembolism?
Odds Ratio: 12.4 (95% CI 3.418–44.744)
Absolute Event Rate: 48.1% vs 7.6%
p-value: p=<0.001
In patients with VTE, tachycardia and tachypnea predict unfavorable outcomes, while diabetes predicts major bleeding and malignancy predicts mortality.
PURPOSE: This study aimed to analyze the clinical outcomes of venous thromboembolism (VTE) patients and identify the risk factors for VTE-related unfavorable outcomes, major bleeding, and 30-day all-cause mortality. MATERIALS AND METHODS: From January 2016 to December 2020, 198 patients with confirmed VTE were enrolled. Potential risk factors for unfavorable outcomes, major bleeding, and all-cause mortality were analyzed. RESULTS: VTE-related unfavorable outcomes developed in 13.1%, while 30-day all-cause mortality was 8.6%. In the multivariate analysis, a pulse ≥110/min and respiratory rate ≥30/min were statistically significant predictors for VTE-related unfavorable outcomes. Diabetes was a significant risk factor for major bleeding. In addition, a history of malignancy, no anticoagulation treatment, and need for mechanical ventilation were significant predictors of all-cause mortality. CONCLUSION: VTE-related mortality and morbidity rates remained high. In cases of tachycardia and tachypnea, early aggressive treatment is needed to prevent unfavorable outcomes. Patients with risk factors should be closely monitored.
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Lee et al. (2021) conducted an observational in Venous thromboembolism (n=198). Tachycardia (pulse ≥110/min) vs. Pulse <110/min was evaluated on VTE-related unfavorable outcomes (OR 12.4, 95% CI 3.418-44.744, p=<0.001). Tachycardia (pulse ≥110/min) significantly increased the risk of VTE-related unfavorable outcomes (OR 12.4) in patients with venous thromboembolism.
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