Various kinds of lasers such as argon, krypton, dye, Nd: YAG and diode have been developed since 1963 whenlaser was used as a photocoagulation source for the first time, and laser photocoagulation is an essential therapyin Ophthalmology now. The major chromophore in the ocular fundus is melanin pigments in the retinalpigment epithelium and hemoglobin in the choriocapillaris. Green and orange lasers are used for retinalphotocoagulation in diabetic retinopathy, retinal tear and other retinal diseases. Red laser is useful for treatingcertain conditions such as choroidal neovascularization embedded in subretinal hemorrhage. Slit lamp deliveryis most popular, but indirect ophthalmoscope and transscleral photocoagulation is useful for retinopathy ofprematurity. New technology such as scanning laser ophthalmoscope delivery and selective retinal pigmentepithelial photocoagulation are investigated now. Laser photocoagulation will not be limited to the traditionalthermal destruction of the tissue but become a more sophisticated treatment modality to selectively manage thetarget cells in the retina.
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Akira Obana (2001) studied this question.
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