Key result
Type 2 diabetes mellitus was associated with a significantly higher rate of transcranial Doppler abnormalities compared to healthy controls (55% vs. 11%, P<0.05).
Why the study?
Does type 2 diabetes mellitus alter cerebral hemodynamics as assessed by transcranial Doppler ultrasound compared to healthy controls?
Case-Control (n=200)
No
Does type 2 diabetes mellitus alter cerebral hemodynamics as assessed by transcranial Doppler ultrasound compared to healthy controls?
Absolute Event Rate: 55% vs 11%
p-value: p=<0.05
Transcranial Doppler ultrasound identifies a significantly higher rate of cerebral hemodynamic abnormalities and increased pulsatility index in patients with type 2 diabetes compared to healthy controls.
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May indicate altered cerebral hemodynamics in type 2 diabetes; leaves open whether transcranial Doppler abnormalities predict clinical events.
Dikanović et al. (2005) conducted a case-control in Type 2 diabetes mellitus (n=200). Type 2 diabetes mellitus vs. Healthy subjects without diabetes mellitus was evaluated on Rate of transcranial Doppler (TCD) abnormalities (p=<0.05). Type 2 diabetes mellitus was associated with a significantly higher rate of transcranial Doppler abnormalities compared to healthy controls (55% vs. 11%, P<0.05).