Study of a patient with recurrent erythema annulare centrifugum of eight years' duration revealed it to be due to hypersensitivity toPenicilliummold of blue cheese. Oral test administration of blue cheese produced a rapid flare and extension of the lesions with a concomitant specific degranulation and decrease in the circulating basophil leukocytes. Complete avoidance of blue cheese has resulted in clinical clearing.
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Walter B. Shelley (1964) studied this question.
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