Key result
The pooled incidence of catheter-related neonatal pericardial effusion is 3.8 per 1000 central catheters placed, with a mortality rate of 27% among affected neonates.
Why the study?
Neonatal pericardial effusion is a severe, rapidly progressive complication of central catheters with high mortality, prompting a need to estimate overall incidence, mortality, and clinical predictors.
What are the incidence, mortality, and predictors of catheter-related pericardial effusion in neonates with central catheters?
Comparison
Predictors and characteristics of catheter-related neonatal pericardial effusion and death
Design
Systematic review and meta-analysis
Authors
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May warrant silicone catheter preference and Seldinger avoidance in neonates; leaves open optimal management pending prospective trials.
Meta-Analysis
What are the incidence, mortality, and predictors of catheter-related pericardial effusion in neonates with central catheters?
Effect estimate: 3.8‰ (95% CI 2.2‰, 6.7‰)
Catheter-related neonatal pericardial effusion carries a high mortality rate of 27%, which may be mitigated by using silicone catheters and performing timely pericardiocentesis when effusion occurs.
Wang et al. (2022) conducted a meta-analysis in Catheter-related neonatal pericardial effusion. Central venous catheters was evaluated on Pooled incidence of catheter-related neonatal pericardial effusion (3.8‰, 95% CI 2.2‰, 6.7‰). The pooled incidence of catheter-related neonatal pericardial effusion is 3.8 per 1000 central catheters placed, with a mortality rate of 27% among affected neonates.
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