Key result
In patients with upper gastrointestinal bleeding and acute myocardial infarction, peak BNP levels were an independent predictor of in-hospital mortality (OR 3.880).
Why the study?
What are the independent predictors of in-hospital mortality in patients with simultaneous upper gastrointestinal bleeding and acute myocardial infarction?
Observational (n=243)
No
What are the independent predictors of in-hospital mortality in patients with simultaneous upper gastrointestinal bleeding and acute myocardial infarction?
Odds Ratio: 3.88 (95% CI 1.761–8.55)
p-value: p=0.001
Age, peak WBC count, minimum platelet count, and peak BNP levels independently predict in-hospital mortality in patients with concurrent UGIB and AMI.
High in-hospital mortality in concurrent UGIB-AMI warrants vigilant monitoring; leaves open prospective validation of identified predictors.
Background/Aims: Patients with simultaneous upper gastrointestinal bleeding (UGIB) and acute myocardial infarction (AMI) have higher mortality than patients with either GIB or AMI. We aimed to assess the incidence and risk factors of in-hospital mortality in patients with UGIB and AMI. Patients and Methods: A total of 243 patients with UGIB and AMI were enrolled during 2012-2017. Clinical and laboratory data were collected and analyzed for clinical characteristics and potential risk factors of in-hospital mortality. Results: /L, P= 0.013). In multivariable logistic analysis, age [OR (95% CI) =1.118 (1.053-1.186), P < 0.001], peak WBC count [OR (95% CI) =1.252 (1.113-1.407), P < 0.001], minimum platelet count [OR (95% CI) = 0.994 (0.989-1.000), P= 0.032], and peak BNP levels [OR (95% CI) =3.880 (1.761-8.550), P= 0.001] were independent predictors of in-hospital mortality. Conclusions: Patients with UGIB and AMI had a high in-hospital mortality, which was independently associated with age, peak WBC count, minimum platelet count, and peak BNP levels.
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Zhang et al. (2018) conducted an observational in Upper gastrointestinal bleeding and acute myocardial infarction (n=243). Peak BNP levels vs. Lower peak BNP levels was evaluated on In-hospital mortality (OR 3.880, 95% CI 1.761-8.550, p=0.001). In patients with upper gastrointestinal bleeding and acute myocardial infarction, peak BNP levels were an independent predictor of in-hospital mortality (OR 3.880).
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