Sulfated Polysaccharide from the Marine Sponge Callyspongia vaginalis

The literature reports several results of chemical investigations from marine ecosystems, which have showed molecules with great biological potential, therefore, its fauna and flora has been target of several studies. Among the marine organisms highlight the sponges, sessile animals, belonging to the poriferous phylum, a profitable source of micro and macromolecules such as polysaccharides, with several biological activities reported in the literature. The chemical investigation of Callyspongia vaginalis led to the isolation of a sulfated polysaccharide. Experiments of hydrolysis, reducing sugars, thermal stability, infrared, and 1 H NMR analyses were performed to characterize the polysaccharide. The ideal time for hydrolysis was 6 hours, presenting a concentration of 4.60 mg / mL of reducing sugar. The polysaccharide showed thermal stability up to about 200 C. This is the first report of polysaccharide in the genus Callyspongia