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February 1, 2016Childhood Obesity

Severe obesity in adolescents was associated with significantly higher odds of cardiometabolic risk factors compared to normal weight, including high blood pressure (OR 5.3; 95% CI 3.8-7.3).

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Why the study?

Does severe obesity increase the odds of cardiometabolic risk factors in youths aged 6-19 years compared to normal weight and moderate obesity?

Population

20,905 youths aged 6-19 years participating in the National Health and Nutrition Examination Surveys…

Comparison

Severe obesity vs Normal weight adolescents and moderately obese…

Design

Cross-sectional

Key result

Severe obesity in adolescents was associated with significantly higher odds of cardiometabolic risk factors compared to normal weight, including high blood pressure (OR 5.3; 95% CI 3.8-7.3).

Authors

LLLinlin LiAPAdriana PérezLWLi‐Tzy Wu

Discussion

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Overview

May support enhanced cardiometabolic screening in severely obese youth; leaves open causality and intervention effects.

Study Design

Type

Cross-Sectional (n=20,905)

Multicenter

Yes

Structured PICO

Does severe obesity increase the odds of cardiometabolic risk factors in youths aged 6-19 years compared to normal weight and moderate obesity?

P
Population
20,905 youths aged 6-19 years from the US National Health and Nutrition Examination Surveys (1999-2012) assessed for the relationship between weight status and cardiometabolic risk factors.
E
Exposure
Severe obesity (defined as BMI ≥120% of 95th percentile of gender-specific BMI-for-age or BMI ≥35 kg/m2)
C
Comparator
Normal weight adolescents and moderately obese adolescents
O
Outcome
Obesity-related cardiometabolic risk factors including blood pressure (BP), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), total cholesterol (TC), triglycerides, and fasting glucose (FG)surrogate

Main Result

Odds Ratio: 5.3 (95% CI 3.8–7.3)

Severe obesity in children and adolescents is associated with a markedly increased risk of cardiometabolic risk factors compared to normal weight and moderate obesity.

Cite This Study

Li et al. (2016) conducted a cross-sectional in Severe obesity (n=20,905). Severe obesity vs. Normal weight was evaluated on High blood pressure (OR 5.3, 95% CI 3.8-7.3). Severe obesity in adolescents was associated with significantly higher odds of cardiometabolic risk factors compared to normal weight, including high blood pressure (OR 5.3; 95% CI 3.8-7.3).

synapsesocial.com/papers/6a97c8c6e6df4f2d12366692https://doi.org/10.1089/chi.2015.0136
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