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March 8, 2017Journal of the Saudi Heart AssociationOpen Access

Effect of acute coronary syndrome patients’ education on adherence to dual antiplatelet therapy

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Key result

Patient education on DAPT improved adherence at 6 months (99.3% vs 94.4%, p=0.016), but this effect was not sustained at 12 months (p=0.443).

Why the study?

Does patient education on coronary artery disease and DAPT improve adherence to DAPT in patients with recent acute coronary syndrome?

Population

321 patients prescribed acetyl salicylic acid and clopidogrel dual antiplatelet therapy within 15 days of an…

Comparison

Education on coronary artery disease and the… vs Education on lifestyle modifications alone.

Design

RCT, randomized into two arms

Follow-up

1 year

Authors

HEHassan El-ToukhyAOAbdullah OmarFortis Escorts Heart InstituteMSManal Abou Samra

Discussion

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Implication

Short-term DAPT adherence gains from ACS education support brief interventions now; leaves open optimal long-term strategies.

Study Design

Type

RCT (n=321)

Structured PICO

Does patient education on coronary artery disease and DAPT improve adherence to DAPT in patients with recent acute coronary syndrome?

P
Population
321 patients prescribed DAPT within 15 days of an ACS event, followed for 1 year.
I
Intervention
Education on coronary artery disease and the importance of sustained platelet inhibition, in addition to education on lifestyle modifications.
C
Comparator
Education on lifestyle modifications alone.
O
Outcome
Adherence to DAPT assessed by pill count at 6 and 12 months.

Main Result

Absolute Event Rate: 99.3% vs 94.4%

p-value: p=0.016

Patient education on DAPT provides only a short-term improvement in adherence, highlighting the need for more effective long-term educational strategies.

Cite This Study

El-Toukhy et al. (2017) conducted an RCT in Acute coronary syndrome (n=321). Patient education on coronary artery disease and DAPT vs. Education on lifestyle modifications only was evaluated on Adherence to DAPT at Month 6 (p=0.016). Patient education on DAPT improved adherence at 6 months (99.3% vs 94.4%, p=0.016), but this effect was not sustained at 12 months (p=0.443).

synapsesocial.com/papers/6a97ca00378ea914c1fad92ehttps://doi.org/10.1016/j.jsha.2017.02.003
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Also Consider

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