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December 1, 1963Circulation

Cardiac Performance after Open Intracardiac Surgery

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Key result

Postoperative open intracardiac surgery patients exhibited wider variations in metabolic rate, hemoglobin, and arterial oxygen than nonsurgical patients, making cardiac output relations less predictable.

Why the study?

How do physiological variables and cardiac performance differ in patients after open intracardiac surgery compared to nonsurgical patients?

Population

Patients after open intracardiac surgery

Design

Cohort

Follow-up

postoperative period

Authors

JKJohn W. KirklinCardiac SurgeryRTRichard A. TheyeBoston University

Discussion

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Implication

Greater variability may reduce reliability of standard cardiac output estimates postoperatively; leaves open need for prospective validation of monitoring strategies.

Study Design

Type

Observational

Structured PICO

How do physiological variables and cardiac performance differ in patients after open intracardiac surgery compared to nonsurgical patients?

P
Population
Patients evaluated for cardiac output and related variables after open intracardiac surgery.
C
Comparator
Nonsurgical patients
O
Outcome
Cardiac output and related variablessurrogate

The study highlights that standard physiological relationships, such as between cardiac output and mixed venous oxygen saturation, are less predictable in the acute postoperative phase following open intracardiac surgery.

Cite This Study

Kirklin et al. (1963) conducted an observational in Open intracardiac surgery. Open intracardiac surgery vs. Nonsurgical patients was evaluated on Cardiac output and related variables. Postoperative open intracardiac surgery patients exhibited wider variations in metabolic rate, hemoglobin, and arterial oxygen than nonsurgical patients, making cardiac output relations less predictable.

synapsesocial.com/papers/6a97ca0cb588d5324d366bf1https://doi.org/10.1161/01.cir.28.6.1061
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1POSTOPERATIVE CARE AFTER WHOLE-BODY PERFUSION AND OPEN INTRACARDIAC OPERATIONS1960 · 28 citations
  2. 2Estimation of Cardiac Output Soon After Intracardiac Surgery with Cardiopulmonary Bypass1959 · 122 citations
  3. 3Physiologic Studies Following Surgical Correction of Ventricular Septal Defect1963 · 25 citations
  4. 4Physiologic Studies Early after Repair of Tetralogy of Fallot1963 · 33 citations
  5. 5Physiologic Studies Following Profound Hypothermia and Circulatory Arrest for Treatment of Intracranial Aneurysm1962 · 23 citations