Key result
Type II hybrid arch repair resulted in similar rates of composite adverse events compared to total arch replacement with frozen elephant trunk (20.6% vs 17.8%; P=0.450).
Why the study?
The objective outcomes comparing type II hybrid arch repair versus total arch replacement with frozen elephant trunk needed to be evaluated.
Does type II hybrid arch repair improve outcomes compared to total arch replacement with frozen elephant trunk in patients undergoing aortic arch repair?
Cohort (n=528)
Does type II hybrid arch repair improve outcomes compared to total arch replacement with frozen elephant trunk in patients undergoing aortic arch repair?
Absolute Event Rate: 20.6% vs 17.8%
p-value: p=0.450
Type II hybrid arch repair and total arch replacement with frozen elephant trunk show no significant differences in early and mid-term composite adverse events, survival, or reintervention rates.
Caution against routine adoption of Type II hybrid repair; leaves open comparative effectiveness in prospective trials.
OBJECTIVES: The aim of this study was to evaluate the objective outcomes of type II hybrid arch repair (HAR) and total arch replacement with frozen elephant trunk (TAR with FET). METHODS: Data from 528 patients who underwent aortic arch repair from January 2017 to June 2019 were collected, which consisted of 175 type II HAR and 353 TAR with FET. The propensity score-matched analysis identified a subgroup of 90 pairs. Perioperative data and mid-term follow-up results were assessed. RESULTS: There was no significant difference in the composite adverse events (type II HAR, 20.6%, 36/175 vs TAR with FET, 17.8%, 63/353, P = 0.450). Multivariable logistic analysis of the 528 patients showed that the procedure type (type II HAR or TAR with FET) was not associated with composite adverse events, 30-day mortality or stroke. The 3-year survival rates were 84.8% in the type II HAR group and 90.1% in the TAR with FET group (P = 0.12). The 3-year reintervention-free rates in the type II HAR and TAR with FET groups were 98.7% and 96.5% (P = 0.22), respectively. After matching, no significant difference was found in the incidence of composite adverse events or the 3-year survival and reintervention-free rates. CONCLUSIONS: No significant clinical differences were found in the early and mid-term outcomes of type II HAR and TAR with FET. The long-term outcomes remain to be investigated. Careful patient selection for individualized approaches is the key to taking full advantage of the 2 surgical procedures.
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Liu et al. (2021) conducted a cohort in aortic arch repair (n=528). Type II hybrid arch repair (HAR) vs. Total arch replacement with frozen elephant trunk (TAR with FET) was evaluated on composite adverse events (p=0.450). Type II hybrid arch repair resulted in similar rates of composite adverse events compared to total arch replacement with frozen elephant trunk (20.6% vs 17.8%; P=0.450).
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