Key result
Oral inoculation with TAstV-2 from PES-affected birds resulted in significantly lower body weight and reduced bursa size at 16 days compared to TAstV-2 from healthy birds or PBS.
Why the study?
Does type-2 turkey astrovirus from PES-affected birds cause more severe clinical signs and growth retardation compared to virus from healthy birds in poults?
Population
90 7-day-old poults, negative for astrovirus, rotavirus, coronavirus, and reovirus by RT-PCR
Comparison
Oral inoculation with turkey astrovirus-positive… vs Negative control given PBS (Group C)
Design
Preclinical, Divided evenly into 3 groups
Follow-up
16 days postinoculation
Authors
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Indicates strain-specific TAstV-2 virulence in poults; leaves open its contribution to PES outbreaks in commercial flocks.
Does type-2 turkey astrovirus from PES-affected birds cause more severe clinical signs and growth retardation compared to virus from healthy birds in poults?
Type-2 turkey astrovirus from PES-affected birds appears more pathogenic, causing significant growth retardation and bursa size reduction compared to strains from healthy birds.
Mor et al. (2011) studied Poult enteritis syndrome (PES) (n=90). TAstV-2 from PES-affected birds vs. TAstV-2 from healthy flocks and PBS was evaluated on Body weight and bursa size at 16 days postinoculation. Oral inoculation with TAstV-2 from PES-affected birds resulted in significantly lower body weight and reduced bursa size at 16 days compared to TAstV-2 from healthy birds or PBS.
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