What question did this study set out to answer?

To determine the epidemiological transmission patterns and serological profiles of hepatitis B virus infection among hospital outpatients.

June 1, 1989Journal of Medical Virology

Epidemiology of hepatitis B in eastern Kenya

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Authors

KHKenneth C. HyamsUnifor JMJohn C. MorrillGates (United States)JWJames N. WoodyInfirmerie Protestante

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Implication

Cross-sectional survey reveals high hepatitis B seroprevalence and early childhood transmission in hospital outpatients, highlighting the need for timely infant vaccination.

Key Points

To determine the epidemiological transmission patterns and serological profiles of hepatitis B virus infection among hospital outpatients.
Conducted a cross-sectional serosurvey of outpatients attending three distinct general hospitals in Mombasa, Kilifi, and Malindi, Kenya.
Sampled N=1,533 individuals (mean age 21.9 ± 13.2 years; range, 4 months to 80 years) and tested sera for HBsAg, anti-HBs, anti-HBc, HBeAg, and anti-delta antibodies.
Evaluated demographic and clinical risk factors for viral marker positivity using multivariate statistical analysis.
Overall, 11.4% of participants tested positive for HBsAg, 56.2% were seropositive for at least one hepatitis B marker, and anti-delta antibodies were detected in 1.2% of HBsAg-positive cases.
Seropositivity increased steadily with age from 20% in children under 4 years old to over 80% in individuals older than 40 years, with 36.0% of HBsAg-positive women of childbearing age harboring HBeAg.
Multivariate regression revealed male sex was independently associated with HBsAg carriage, while increasing age and parity were significantly associated with general hepatitis B seropositivity.

Cite This Study

Hyams et al. (1989) studied this question.

synapsesocial.com/papers/6a97d55ea2c7923eae15dfe1 https://doi.org/10.1002/jmv.1890280210

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Implication

Cross-sectional survey reveals high hepatitis B seroprevalence and early childhood transmission in hospital outpatients, highlighting the need for timely infant vaccination.

Epidemiology of hepatitis B in eastern Kenya

Discussion

Member takes

Implication

Key Points

Cite This Study

Epidemiology of hepatitis B in eastern Kenya

Discussion

Member takes

Implication

Key Points

Cite This Study

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