The modulatory effects of lead toxicity by Spirulina fusiformis (Oscillatoreaceae) were observed on the testes of Swiss albino mice at a dose of 800 mg/kg body weight. The Spirulina fusiformis was non-toxic at the dose given. A significant enhancement in the survival time was observed in the pre- and post-treated Spirulina group compared with the control (lead treated) group. Lead induced toxicity was also reduced in terms of testes weight, animal weight, tubular diameter in the pre Spirulina treated group. The modulatory effects of Spirulina may be attributed to the presence of the antioxidants, beta-carotene and SOD enzyme.
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Shastri et al. (1999) studied this question.
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