Key result
Two pediatric cases of rhabdomyolysis presented with severe acute onset, including acute renal failure and electrolyte imbalances, and were diagnosed using simple laboratory tests.
Case Report (n=2)
Rhabdomyolysis in pediatric patients can present severely with acute renal failure and hypertension, but is readily diagnosed via simple laboratory tests like serum creatine kinase.
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We report two pediatric cases of rhabdomyolysis. This disease involves the destruction of skeletal muscle, which can present with myalgia and a brown-pigmented urine. The first patient presented with acute renal failure, hypertension, and hyponatremia. The second patient was pyrexic, hypernatremic, and hypokalemic, and later developed hypertension. Evidence of rhabdomyolysis in both patients included dark, o-tolidine-positive urine, granular casts in the urinary sediment, and grossly increased activities of creatine kinase (greater than 60 000 U/L) in serum. An uncommonly recognized entity in the pediatric age group, rhabdomyolysis often presents as an acute disease with severe onset but can be diagnosed with relatively simple laboratory tests.
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Alerts clinicians to severe pediatric rhabdomyolysis with renal failure; case reports extend awareness but leave open larger validation studies.
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Goldsmith et al. (1985) conducted a case report in Rhabdomyolysis (n=2). Two pediatric cases of rhabdomyolysis presented with severe acute onset, including acute renal failure and electrolyte imbalances, and were diagnosed using simple laboratory tests.
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