Case report describes squamous cell carcinoma of the external auditory canal after nasopharyngeal cancer radiotherapy, highlighting diagnostic challenges of radiation-associated secondary tumors.
We describe a case of a 64-year-old man presenting with squamous cell carcinoma of the external auditory canal as a second primary malignancy after treatment of nasopharyngeal carcinoma, including conventional radiotherapy.Squamous cell carcinoma of the external auditory canal is a rare malignancy, with radiationrelated cases even rarer.Management of this malignancy remains difficult due to the critical anatomical location and invasive nature, particularly in advanced stages.Several hypotheses have been advanced to explain the occurrence of second primary malignancies.We discuss this unusual malignancy, highlighting the diagnostic challenges encountered and the potential risk factors associated with second primary cancers.
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Jabri et al. (2026) studied this question.
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