What does this research mean for the field?

Ethanol extracts of Salvia officinalis and Thymus sipyleus exhibit stronger α-glucosidase inhibitory activity than the synthetic reference inhibitor acarbose, indicating their potential as natural antidiabetic agents. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate and compare the in vitro α-glucosidase inhibitory potential of ethanol extracts from Salvia officinalis, Thymus sipyleus, and Lavandula stoechas against the standard drug acarbose.

September 2, 2026Cumhuriyet Science JournalOpen Access

Comparative α-Glucosidase Inhibitory Activity of Salvia officinalis L., Thymus sipyleus Boiss., and Lavandula stoechas L.

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SASevgi Altın

Discussion

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Overview

In vitro comparative assay demonstrates potent alpha-glucosidase inhibition by medicinal plant extracts, suggesting promising natural alternatives for postprandial hyperglycemia management.

Key Points

To evaluate and compare the in vitro α-glucosidase inhibitory potential of ethanol extracts from Salvia officinalis, Thymus sipyleus, and Lavandula stoechas against the standard drug acarbose.
Prepared ethanol extracts from three Lamiaceae species: Salvia officinalis L., Thymus sipyleus Boiss., and Lavandula stoechas L.
Measured in vitro α-glucosidase inhibitory activity and quantified potency using half-maximal inhibitory concentration (IC50) values compared to acarbose.
Salvia officinalis exhibited the highest inhibitory activity with an IC50 of 2.44 ± 0.086 µg/mL, followed by Thymus sipyleus with an IC50 of 2.71 ± 0.40 µg/mL.
Both S. officinalis and T. sipyleus demonstrated greater inhibitory potency than the standard reference inhibitor acarbose (IC50: 2.85 ± 0.23 µg/mL).
Lavandula stoechas displayed lower inhibitory activity relative to the other tested extracts, yielding an IC50 of 5.68 ± 0.05 µg/mL.

Cite This Study

Sevgi Altın (2026) studied this question.

synapsesocial.com/papers/6a97e249c562ede874ec64f8 https://doi.org/10.17776/csj.1919914

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September 2, 2026Cumhuriyet Science JournalOpen Access

Comparative α-Glucosidase Inhibitory Activity of Salvia officinalis L., Thymus sipyleus Boiss., and Lavandula stoechas L.

View Full Paper

Ask AI

Bookmark

Authors

SASevgi Altın

Discussion

Member takes

Overview

In vitro comparative assay demonstrates potent alpha-glucosidase inhibition by medicinal plant extracts, suggesting promising natural alternatives for postprandial hyperglycemia management.

Key Points

To evaluate and compare the in vitro α-glucosidase inhibitory potential of ethanol extracts from Salvia officinalis, Thymus sipyleus, and Lavandula stoechas against the standard drug acarbose.
Prepared ethanol extracts from three Lamiaceae species: Salvia officinalis L., Thymus sipyleus Boiss., and Lavandula stoechas L.
Measured in vitro α-glucosidase inhibitory activity and quantified potency using half-maximal inhibitory concentration (IC50) values compared to acarbose.
Salvia officinalis exhibited the highest inhibitory activity with an IC50 of 2.44 ± 0.086 µg/mL, followed by Thymus sipyleus with an IC50 of 2.71 ± 0.40 µg/mL.
Both S. officinalis and T. sipyleus demonstrated greater inhibitory potency than the standard reference inhibitor acarbose (IC50: 2.85 ± 0.23 µg/mL).
Lavandula stoechas displayed lower inhibitory activity relative to the other tested extracts, yielding an IC50 of 5.68 ± 0.05 µg/mL.

Cite This Study

Sevgi Altın (2026) studied this question.

synapsesocial.com/papers/6a97e249c562ede874ec64f8 https://doi.org/10.17776/csj.1919914

View Full Paper

Ask AI

Bookmark