What does this research mean for the field?

Clinical management and diagnostic testing of community-acquired respiratory viral infections in hematology and transplant patients vary significantly, with influenza A management being consistent while RSV, HMPV, and HPIV approaches show substantial heterogeneity. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Evaluate clinician awareness, diagnostic testing strategies, and intended treatment approaches for community-acquired respiratory viruses in haematology and haematopoietic cell transplantation settings.

September 2, 2026DiagnosticsOpen Access

Clinician-Reported Respiratory Viral Testing and Intended Management of Community-Acquired Respiratory Viral Infections in Haematology and Haematopoietic Cell Transplantation: An International Exploratory Survey

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Authors

JTJohan Du ToitUniversity of the Witwatersrand TNTobias R. NeijzenSpaarne Ziekenhuis SBSjoerd van der BieErasmus MC

Discussion

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Implication

International survey reveals widespread variation in respiratory viral management among haematology and transplant clinicians, highlighting a lack of standardized clinical consensus.

Key Points

Evaluate clinician awareness, diagnostic testing strategies, and intended treatment approaches for community-acquired respiratory viruses in haematology and haematopoietic cell transplantation settings.
Administered an international electronic survey using non-probability convenience sampling to haematology, oncology, intensive care, and emergency medicine physicians across 26 countries (N=98).
Assessed testing approaches and intended interventions using four standardized clinical vignettes representing human metapneumovirus (HMPV), respiratory syncytial virus (RSV), human parainfluenza virus (HPIV), and influenza A virus (IAV).
Influenza A virus management showed the highest consistency among clinicians, linked directly to routine vaccination availability, targeted antiviral treatment, and post-exposure prophylaxis.
Treatment approaches for RSV exhibited high heterogeneity, with systemic ribavirin considered by 46.9% (45/96) of respondents, including 35.4% (34/96) who would guide administration using an immunodeficiency scoring system.
In the absence of established pathogen-specific therapies for HMPV and HPIV, respondents reported primarily using supportive care, immunoglobulin replacement, and infection-control measures.

Cite This Study

Toit et al. (2026) studied this question.

synapsesocial.com/papers/6a97e275c562ede874ec69be https://doi.org/10.3390/diagnostics16172786

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Implication

International survey reveals widespread variation in respiratory viral management among haematology and transplant clinicians, highlighting a lack of standardized clinical consensus.

Clinician-Reported Respiratory Viral Testing and Intended Management of Community-Acquired Respiratory Viral Infections in Haematology and Haematopoietic Cell Transplantation: An International Exploratory Survey

Discussion

Member takes

Implication

Key Points

Cite This Study

Clinician-Reported Respiratory Viral Testing and Intended Management of Community-Acquired Respiratory Viral Infections in Haematology and Haematopoietic Cell Transplantation: An International Exploratory Survey

Discussion

Member takes

Implication

Key Points

Cite This Study

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