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Case report documents new-onset ankylosing spondylitis in a 32-year-old male following Pfizer-BioNTech vaccination, suggesting potential immune-mediated reactions driven by molecular mimicry.
Autoimmune/autoinflammatory diseases, including rheumatic diseases, may occur and/or flare up after COVID-19 vaccines, due to the molecular similarities between viral antigens and antigenic structures in the human body. In this case, the aim is to present the diagnostic process of Ankylosing Spondylitis and the initiation of treatment of a 32-year-old young male patient whose complaints started after the Pfizer-BioNTech COVID-19 vaccine.
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Tuğba Özüdoğru Çelik (2026) studied this question.
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