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September 2, 2026Journal of Conservative Dentistry and Endodontics

Getting your publication right – Part 3 structuring a research manuscript: A guide to writing clinical trials

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Authors

AMAditya MitraRKR. S. Mohan KumarSSShishir Singh

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Overview

Narrative review demonstrates essential frameworks for structuring clinical trial manuscripts in academic healthcare, highlighting strategies to improve transparency and publication success.

Key Points

  • Provide a comprehensive guide for researchers on structuring, writing, and successfully publishing clinical trial manuscripts in evidence-based healthcare.
  • Conducted a narrative review synthesizing recommendations across the publication lifecycle from protocol design to peer review.
  • Evaluated critical reporting standards, including the Consolidated Standards of Reporting Trials (CONSORT) framework, trial registration, and ethical clearance.
  • Identified essential components for successful publication, including clear research questions, adherence to CONSORT reporting guidelines, and robust statistical reporting.
  • Highlighted major drivers of manuscript rejection such as inadequate methodology, poor data presentation, lack of transparency, and publication bias.

Cite This Study

Mitra et al. (2026) studied this question.

synapsesocial.com/papers/6a97e28dc562ede874ec6a7ehttps://doi.org/10.4103/jcde.jcde_794_26
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