What does this research mean for the field?

Pseudomonas aeruginosa and Staphylococcus aureus are the predominant bacterial isolates in refractory chronic suppurative otitis media, frequently showing susceptibility to meropenem and amikacin and resistance to ciprofloxacin, erythromycin, and tetracycline. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To identify the bacterial pathogens causing refractory chronic suppurative otitis media and describe their antimicrobial susceptibility and resistance profiles in patients with persistent otorrhea.

September 2, 2026HRU International Journal of Dentistry and Oral Research

Microbiological Profile and Recorded Antimicrobial Susceptibility Findings in Patients with Refractory Chronic Suppurative Otitis Media: A Retrospective Study

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Authors

SEServet ErdemesHarran University

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Implication

Retrospective study reveals predominant pathogens and resistance patterns in refractory chronic suppurative otitis media, highlighting the need for targeted therapy.

Key Points

To identify the bacterial pathogens causing refractory chronic suppurative otitis media and describe their antimicrobial susceptibility and resistance profiles in patients with persistent otorrhea.
Retrospective analysis of N=185 patients treated for refractory chronic suppurative otitis media (persistent active otorrhea after two 14-day antibiotic courses) at a tertiary care university hospital between 2021 and 2023.
Ear cultures were obtained 7 days after the final antibiotic course, identified using conventional methods and the VITEK system, and tested for antimicrobial susceptibility using Kirby-Bauer disk diffusion per EUCAST criteria.
Following the exclusion of 19 negative cultures and 15 fungal isolates, 151 patients with bacterial growth were analyzed (mean age 33.4 ± 21.4 years; 65.6% female).
Pseudomonas aeruginosa (n=92; 60.9%) and Staphylococcus aureus (n=36; 23.8%) were the predominant bacterial pathogens isolated.
Meropenem (n=72) and amikacin (n=63) were the most frequently recorded susceptible agents, whereas ciprofloxacin (n=49), erythromycin (n=47), and tetracycline (n=44) were the most frequently recorded resistant agents.

Cite This Study

Servet Erdemes (2026) studied this question.

synapsesocial.com/papers/6a97e28dc562ede874ec6c2e https://doi.org/10.61139/ijdor.2001594

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Implication

Retrospective study reveals predominant pathogens and resistance patterns in refractory chronic suppurative otitis media, highlighting the need for targeted therapy.

Microbiological Profile and Recorded Antimicrobial Susceptibility Findings in Patients with Refractory Chronic Suppurative Otitis Media: A Retrospective Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Microbiological Profile and Recorded Antimicrobial Susceptibility Findings in Patients with Refractory Chronic Suppurative Otitis Media: A Retrospective Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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