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September 2, 2026Discover Artificial IntelligenceOpen Access

Artificial intelligence approaches for pollutant assessment and environmental toxicology

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Authors

EBEhsan Ghassemi BarghiFMFarzaneh MotafeghiJGJafar Gholami Gharab

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Overview

Narrative review demonstrates predictive artificial intelligence capabilities in chemical hazard and exposure assessment, suggesting AI complements rather than replaces experimental toxicology.

Key Points

  • To review the applications, current limitations, and regulatory potential of predictive artificial intelligence across chemical hazard assessment, exposure modeling, and environmental toxicology.
  • Conducted a narrative review synthesizing machine-learning and deep-learning approaches in pollutant hazard assessment and monitoring.
  • Evaluated the computational integration of chemical descriptors, high-throughput screening data, multi-omics profiles, and sensor measurements.
  • Machine-learning and deep-learning models support chemical prioritization, mechanism-informed risk assessment, and reduced dependence on animal testing.
  • Model accuracy and adoption remain constrained by dataset bias, domain shift, limited external validation, and poor transferability across varied chemical classes and ecosystems.
  • Current evidence supports deploying artificial intelligence as a complementary screening tool alongside physical testing rather than as a standalone replacement for experimental toxicology.

Cite This Study

Barghi et al. (2026) studied this question.

synapsesocial.com/papers/6a97e29ec562ede874ec6ce3https://doi.org/10.1007/s44163-026-02126-x
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