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September 2, 2026ChemistrySelect

Sustainable Plant‐Derived Polymeric Materials‐Based Nanocarriers for Targeted Drug Delivery of Breast Cancer Therapeutics: State‐of‐the‐Art Review

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Authors

SKSelvaraj KunjiappanAlliance UniversityPPParasuraman PavadaiM S Ramaiah University of Applied SciencesDMDevika Muraleedharan

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Overview

Narrative review demonstrates plant-derived polymeric nanocarriers enhance targeted drug delivery in breast cancer, highlighting sustainable strategies to reduce toxicity.

Key Points

  • To review recent advances in plant-derived polymeric nanocarriers and assess their potential for targeted, low-toxicity chemotherapeutic drug delivery in breast cancer.
  • Synthesized literature on natural plant-derived polymers, focusing on polysaccharides, proteins, and gums utilized for nanoparticle assembly.
  • Evaluated physicochemical encapsulation methods for hydrophobic and hydrophilic anticancer drugs, alongside surface functionalization strategies for stimuli-triggered drug release.
  • Plant-derived polymers self-assemble into biocompatible nanocarriers capable of shielding chemotherapeutics from enzymatic degradation, ultraviolet light, gastric acid, and pH shifts.
  • Surface-modified plant biopolymer nanoparticles exhibit extended systemic circulation, selective tumor targeting, and controlled stimuli-responsive release while displaying minimal intrinsic cytotoxicity.

Cite This Study

Kunjiappan et al. (2026) studied this question.

synapsesocial.com/papers/6a97e2b1c562ede874ec6e4chttps://doi.org/10.1002/slct.74002
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Also Consider

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  1. 1Current Insights into Polymeric Nanocarriers for Delivery of Phytomedicines in Breast Cancer Therapy2025
  2. 2Recent Advances in Polymeric Nanocarriers for Breast Cancer Drug Delivery2026
  3. 3New developments in the nanocarrier-based drug delivery system for the treatment of breast cancer2025
  4. 4Comprehensive scientific insights on plant inspired nano therapeutics as the missing piece of the breast cancer puzzle2026
  5. 5Amino Acid Polymer-Based Nano-Carriers for Targeted Drug Delivery in Breast Cancer Therapy: Mechanisms, Applications, and Future Perspectives2025