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September 2, 2026Medical Journal of Western Black SeaOpen Access

Transitioning from open to laparoscopic radical prostatectomy: Safety and feasibility during the learning curve

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Authors

YAYavuz AydınYAYiğit AtasoyRGReha Girgin

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Overview

Cohort study demonstrates reduced blood loss and faster recovery with laparoscopic versus open prostatectomy during the learning curve, indicating early procedure safety.

Key Points

  • To evaluate the safety, feasibility, and functional and oncological outcomes during the institutional transition from open retropubic to laparoscopic radical prostatectomy.
  • Retrospective analysis of prospectively collected data from 33 prostate cancer patients undergoing laparoscopic radical prostatectomy (n=12) or open retropubic radical prostatectomy (n=21) between January and June 2025.
  • Assessed perioperative parameters, complications via Clavien-Dindo and Satava classifications, urinary continence via ICIQ-SF (score ≤5 or no pad), and erectile function via IIEF-5 scores (potency defined as ≥17).
  • Laparoscopic radical prostatectomy showed significantly lower estimated blood loss (660.5±221.4 vs 1100±528.1 mL, p=0.021), lower transfusion rates (25.0% vs 71.4%, p=0.027), shorter drain removal times (median 2 vs 4 days, p=0.002), and shorter hospital stays (median 3 vs 4 days, p=0.006).
  • Laparoscopic surgery achieved significantly higher early continence rates at 1 month (33.3% vs 4.8%, p=0.029) and higher median IIEF-5 potency scores at 3 months (10.5 vs 8, p=0.020) and 6 months (13.5 vs 9, p=0.030).
  • Complication rates (16.7% vs 9.5%, p=0.708), positive surgical margins (33.3% vs 66.7%, p=0.137), and biochemical recurrence rates (8.3% vs 4.8%, p=0.685) did not differ significantly between laparoscopic and open procedures.

Cite This Study

Aydın et al. (2026) studied this question.

synapsesocial.com/papers/6a97e2d9c562ede874ec7388https://doi.org/10.29058/mjwbs.1891824
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Classification of Surgical Complications2004 · 31,594 citations
  2. 2Retropubic Prostatectomy1948 · 49 citations
  3. 3Systematic review and economic modelling of the relative clinical benefit and cost-effectiveness of laparoscopic surgery and robotic surgery for removal of the prostate in men with localised prostate cancer.2012 · 262 citations