Key result
PCOS linked to ~150% higher MI risk and increased stroke risk.
Why the study?
Polycystic ovary syndrome carries significant cardiometabolic abnormalities beyond reproductive manifestations, but current risk stratification tools inadequately account for it and cardiology guidelines have not formally designated it as a risk-enhancing condition.
Design
Focused narrative review
Authors
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Supports PCOS inclusion in CV risk assessment; challenges guidelines' omission of formal risk-enhancing designation.
Odds Ratio: 2.5
PCOS is associated with significant cardiometabolic abnormalities and increased risk of myocardial infarction and stroke, highlighting the need for improved cardiovascular risk stratification in this population.
Moore et al. (2026) conducted a review in Polycystic ovary syndrome (PCOS). Polycystic ovary syndrome vs. Controls was evaluated on Myocardial infarction and stroke (OR 2.50 for myocardial infarction and 1.71 for stroke). Polycystic ovary syndrome is associated with a substantial metabolic burden and increased cardiovascular risk, including pooled odds ratios of 2.50 for myocardial infarction and 1.71 for stroke.
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